Article

P2X7R promotes angiogenesis and tumor-associated macrophage recruitment by regulating the NF-κB signaling pathway in colorectal cancer cells

2020-05-11

Abstract excerpt

<h4>Background: </h4> Overexpression of P2 × 7R has been observed in several tumors and is related to cancer advancement and metastasis. However, the role of P2 × 7R in colorectal cancer (CRC) patients is not well understood. Methods In the current study, overexpression of P2 × 7R and the effects at the molecular and functional levels in CRC were assessed in a mouse orthotopic model. Functional assays, such as th...

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Literature Corpus work: a19e24be-a769-59e0-90fa-9ca4d21b1df8
DOI: 10.21203/rs.3.rs-27043/v1

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