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Article

Clinical significance of FBXW7 tumor suppressor gene mutations and expression in human colorectal cancer: a systemic review and meta-analysis.

BMC cancer - 3 Jul 2021

Shang Wei, Yan Chuanwang, Liu Ran, Chen Lili, Cheng Dongdong, Hao Liang, Yuan Wenguang, Chen Jingbo, Yang Hui

Abstract excerpt

BACKGROUND: Various studies investigating the clinical significance of FBXW7 mutation and/or expression have yielded inconclusive results in colorectal cancer (CRC) patients. Therefore, the present meta-analysis summarizes previous evidence and evaluates the clinical significance, including the prognostic role, of FBXW7 status in CRCs. METHODS: The meta-analysis was conducted by searching the databases of PubMed,...

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Identifiers

PMID: 34217244
DOI: 10.1186/s12885-021-08535-8
PMCID: PMC8254329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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