Article

<i>Pten</i> and <i>Dicer1</i> loss causes poorly-differentiated endometrial adenocarcinoma in mice

2020-03-13

Abstract excerpt

Endometrial cancer remains the most common gynecological malignancy in the United States. While the loss of the tumor suppressor, PTEN (phosphatase and tensin homolog), is well studied in endometrial cancer, recent studies suggest that DICER1 , the endoribonuclease responsible for miRNA genesis, also plays a significant role in endometrial adenocarcinoma. In an endometrial adenocarcinoma mouse model, which has a...

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Literature Corpus work: 88f4eefd-dcfc-5825-8908-9247be602aec
DOI: 10.1101/2020.03.12.989087

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