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Article

Deletion of Dicer in Somatic Cells of the Female Reproductive Tract Causes Sterility

8 Aug 2008

Abstract excerpt

Dicer is an evolutionarily conserved ribonuclease III that is necessary for microRNA (miRNA) processing and the synthesis of small interfering RNAs from long double-stranded RNA. Although it has been shown that Dicer plays important roles in the mammalian germline and early embryogenesis, the functions of Dicer-dependent pathways in the somatic cells of the female reproductive tract are unknown. Using a...

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Identifiers

PMID: 18687735
DOI: 10.1210/me.2008-0142

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