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Article

PI3K/PTEN/AKT Genetic Mouse Models of Endometrial Carcinoma.

Advances in experimental medicine and biology - 1 Jan 2017

Joshi Ayesha, Ellenson Lora Hedrick

Abstract excerpt

The PI3K/PTEN/AKT pathway is the most frequently mutated pathway in endometrial carcinoma. Mouse models are invaluable tools to understand, at the molecular level, the contributions of components of this pathway towards initiation and progression of endometrial carcinoma. This chapter summarizes results of germline and tissue specific knockout mouse models generated to understand how mutations in components of...

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Share to Class I Phosphatidylinositol 3-Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

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Source

Identifiers

PMID: 27910071
DOI: 10.1007/978-3-319-43139-0_9

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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