Article

fastGxE: Powering genome-wide detection of genotype-environment interactions in biobank studies

2025-03-20

Abstract excerpt

<title>Abstract</title> <p>Traditional genome-wide association studies (GWAS) have primarily focused on detecting main genotype effects, often overlooking genotype-environment interactions (GxE), which are essential for understanding context-specific genetic effects and refining disease etiology. Here, we present fastGxE, a scalable and effective genome-wide GxE method designed to identify genetic variants that i...

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Literature Corpus work: 22d98506-bdbe-5233-9e0e-00a1626d2841
DOI: 10.21203/rs.3.rs-5952773/v1

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