Article

Predicting transcription factor activity using prior biological information

2022-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Transcription factors are critical regulators of cellular gene expression programs. Disruption of normal transcription factor regulation is associated with a broad range of diseases. In order to understand the mechanisms that underly disease pathogenesis, it is critical to detect aberrant transcription factor activity. We have developed Priori, a computational method to predict transcription fac...

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Literature Corpus work: 88d0871f-018e-5350-aebe-74101c4a540b
DOI: 10.1101/2022.12.16.520295

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