Article

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

2021-09-05

Abstract excerpt

<h4>Background</h4> Several human B-cell subpopulations are recognized in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their immunoglobulin heavy chain (IgH) repertoire. <h4>Methods</h4> Here, we sequenced the IgH reper...

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Literature Corpus work: 88a9785c-06df-505f-b43f-b8a29dcd7e65
DOI: 10.1101/2021.09.01.458522

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