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A Public Database of Memory and Naive B-Cell Receptor Sequences

11 Aug 2016

Abstract excerpt

The vast diversity of B-cell receptors (BCR) and secreted antibodies enables the recognition of, and response to, a wide range of epitopes, but this diversity has also limited our understanding of humoral immunity. We present a public database of more than 37 million unique BCR sequences from three healthy adult donors that is many fold deeper than any existing resource, together with a set of online tools...

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PMID: 27513338
DOI: 10.1371/journal.pone.0160853

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