Article

EndoC-βH1 multi-genomic profiling defines gene regulatory programs governing human pancreatic β cell identity and function

2018-08-23

Abstract excerpt

<h4>SUMMARY</h4> EndoC-βH1 is emerging as a critical human beta cell model to study the genetic and environmental etiologies of beta cell function, especially in the context of diabetes. Comprehensive knowledge of its molecular landscape is lacking yet required to fully take advantage of this model. Here, we report extensive chromosomal (spectral karyotyping), genetic (genotyping), epigenetic (ChIP-seq, ATAC-seq)...

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Literature Corpus work: 8894682c-a504-5ddc-b64f-c0b38f70300a
DOI: 10.1101/399139

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