Article

Implications of noncoding regulatory functions in the development of insulinomas

2024-01-25

Abstract excerpt

<h4>Summary</h4> Insulinomas are rare neuroendocrine tumours arising from the pancreatic β-cells. While retaining the ability to produce insulin, insulinomas feature aberrant proliferation and altered hormone secretion resulting in failure to maintain glucose homeostasis. With the aim of uncovering the role of noncoding regulatory regions and their aberrations to the development of these tumors, we coupled epigen...

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Literature Corpus work: 1a0195c8-8168-5373-b6b3-8b8ca1c4b92a
DOI: 10.1101/2024.01.23.576802

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