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Article

Networking in the nucleus: a spotlight on LEM-domain proteins.

Current opinion in cell biology - 1 Jun 2015

Barton Lacy J, Soshnev Alexey A, Geyer Pamela K

Abstract excerpt

Proteins resident in the inner nuclear membrane and underlying nuclear lamina form a network that regulates nuclear functions. This review highlights a prominent family of nuclear lamina proteins that carries the LAP2-emerin-MAN1-domain (LEM-D). LEM-D proteins share an ability to bind lamins and tether repressive chromatin at the nuclear periphery. The importance of this family is underscored by findings that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25863918
DOI: 10.1016/j.ceb.2015.03.005
PMCID: PMC4522374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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