Article

CGGBP1-dependent CTCF-binding sites restrict ectopic transcription

2020-11-10

Abstract excerpt

Binding sites of the chromatin regulator protein CTCF function as important landmarks in the human genome. The recently characterized CTCF-binding sites at LINE-1 repeats depend on another repeat-regulatory protein CGGBP1. These CGGBP1-dependent CTCF-binding sites serve as potential barrier elements for epigenetic marks such as H3K9me3. Such CTCF-binding sites are associated with asymmetric H3K9me3 levels as well...

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Literature Corpus work: 8850cd77-26e0-596a-9716-a1348a8d49d9
DOI: 10.1101/2020.11.09.375782

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