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Article

Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression.

Nucleic acids research - 15 Feb 2003

Yu Qun, Qiu Runxiang, Foland Travis B, Griesen Dan, Galloway Carl S, Chiu Ya-Hui, Sandmeier Joseph, Broach James R, Bi Xin

Abstract excerpt

Barrier elements that are able to block the propagation of transcriptional silencing in yeast are functionally similar to chromatin boundary/insulator elements in metazoans that delimit functional chromosomal domains. We show that the upstream activating sequences of many highly expressed ribosome protein genes and glycolytic genes exhibit barrier activity. Analyses of these barriers indicate that binding sites...

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Identifiers

PMID: 12582242
DOI: 10.1093/nar/gkg200
PMCID: PMC150219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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