Article

Deciphering Cellular Ecosystems Driving Tumor Progression and Immune Escape from Spatial Transcriptomics and Single-Cell with COMPOTES

2025-10-27

Abstract excerpt

Cell-cell communication is central to understanding the complex interactions within the tumor microenvironment. However, current methods fail to identify recurrent communication patterns across patient cohorts from spatial transcriptomics, as they are often limited to single samples or lack essential spatial context. Yet this is essential for understanding how local environments influence cell phenotype and states...

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Literature Corpus work: 884053ae-f4b5-5d07-8f56-2865c0128dc5
DOI: 10.1101/2025.10.27.684744

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