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STARComm Scalably Detects Emergent Modules of Spatial Cell-Cell Communication in Inflammation and Cancer

2025-08-11

Abstract excerpt

<h4>ABSTRACT</h4> In humans, cell-cell communication orchestrates tissue organization, immune coordination, and repair, yet spatially mapping these interactions remains a challenge for biology. We introduce STARComm, a scalable-interpretable computational method that identifies Multicellular Communication Interaction Modules (MCIMs) by detecting spatially co-located receptor-ligand activity from high-plex spatial...

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Literature Corpus work
19972582-ba62-515a-92f1-232c9c26a4ef
DOI
10.1101/2025.08.07.669133
Open publication

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STARComm Scalably Detects Emergent Modules of Spatial Cell-Cell Communication in Inflammation and CancerDOI 10.1101/2025.08.07.669133
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