Article

Path to drugging functional clones of luminal breast cancers using in-depth proteomics with spatially resolved mass spectrometry guided by MALDI imaging

2021-02-19

Abstract excerpt

Integrating tumor heterogeneity in the drug discovery process is a key challenge to tackle breast cancer resistance. Identifying protein targets for functionally distinct tumor clones is particularly important to tailor therapy to the heterogeneous tumor subpopulations. For this purpose, we performed an unsupervised, label-free, spatially resolved shotgun proteogenomic guided by MALDI mass spectrometry imaging (MS...

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Literature Corpus work: 883e8c97-b2e4-5a3c-9e17-46095287fa7e
DOI: 10.1101/2021.02.16.21251694

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Path to drugging functional clones of luminal breast cancers using in-depth proteomics with spatially resolved mass spectrometry guided by MALDI imagingDOI 10.1101/2021.02.16.21251694Read

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