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Article

De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry.

The Journal of pathology - 1 Jan 2015

Balluff Benjamin, Frese Christian K, Maier Stefan K, Schöne Cédrik, Kuster Bernhard, Schmitt Manfred, Aubele Michaela, Höfler Heinz, Deelder André M, Heck Albert, Hogendoorn Pancras C W, Morreau Johannes, Maarten Altelaar A F, Walch Axel, McDonnell Liam A

Abstract excerpt

An essential and so far unresolved factor influencing the evolution of cancer and the clinical management of patients is intratumour clonal and phenotypic heterogeneity. However, the de novo identification of tumour subpopulations is so far both a challenging and an unresolved task. Here we prese...

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PMID: 25201776
DOI: 10.1002/path.4436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25201776-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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