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Article

The Proteomic Landscape of Triple-Negative Breast Cancer

1 Apr 2015

Abstract excerpt

Triple-negative breast cancer is a heterogeneous disease characterized by poor clinical outcomes and a shortage of targeted treatment options. To discover molecular features of triple-negative breast cancer, we performed quantitative proteomics analysis of twenty human-derived breast cell lines and four primary breast tumors to a depth of more than 12,000 distinct proteins. We used this data to identify breast...

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PMID: 25892236
DOI: 10.1016/j.celrep.2015.03.050

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