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Breast cancer patient-derived microtumors resemble tumor heterogeneity and enable protein-based stratification and functional validation of individualized drug treatment

2023-04-12

Abstract excerpt

<title>Abstract</title> <p>Despite tremendous progress in deciphering breast cancer at the genomic level, the pronounced heterogeneity remains a major obstacle to the advancement of novel and more effective treatment approaches. Frequent treatment failure and the development of treatment resistance highlight the need for patient-derived tumor models that reflect the individual tumors of breast cancer patients and...

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Literature Corpus work
5981bed8-1c66-5cb0-9658-e4ced643cb0f
DOI
10.21203/rs.3.rs-2781727/v1
Open publication

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