Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

1 Feb 2022

Abstract excerpt

Mechanisms of therapeutic resistance and vulnerability evolve in metastatic cancers as tumor cells and extrinsic microenvironmental influences change during treatment. To support the development of methods for identifying these mechanisms in individual people, here we present an omic and multidimensional spatial (OMS) atlas generated from four serial biopsies of an individual with metastatic breast cancer during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35243422
DOI: 10.1016/j.xcrm.2022.100525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancerPMID 35243422Read ↗

An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast CancerSemantic proximity Read ↗

Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient.Semantic proximity Read ↗

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistanceSemantic proximity Read ↗

Spatial Transcriptomics in Breast Cancer Reveals Tumour Microenvironment-Driven Drug Responses and Clonal Therapeutic HeterogeneitySemantic proximity Read ↗

Serial Spatial Transcriptomics Reveal Divergent Routes to Therapy Resistance in Metastatic Breast CancerSemantic proximity Read ↗

MOSAIC: Intra-tumoral heterogeneity characterization through large-scale spatial and cell-resolved multi-omics profilingSemantic proximity Read ↗

Longitudinal and multimodal auditing of tumor adaptation to CDK4/6 inhibitors in HR+ metastatic breast cancersSemantic proximity Read ↗

Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes.Semantic proximity Read ↗

Multiplatform Analysis of Primary and Metastatic Breast Tumors from the AURORA US Network identifies microenvironment and epigenetics drivers of metastasisSemantic proximity Read ↗

The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profileSemantic proximity Read ↗

Multiomics insights on the onset, progression, and metastatic evolution of breast cancerSemantic proximity Read ↗

SMART: A Spatio-Molecular Atlas of Response Trajectories in Triple-Negative Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.