Article

<i>Streptococcus pneumoniae</i> infection promotes histone H3 dephosphorylation by modulating host PP1 phosphatase

2020-01-14

Abstract excerpt

<h4>Summary</h4> Pathogenic bacteria can alter host gene expression through post-translational modifications of histones. We show for the first time that a natural colonizer, Streptococcus pneumoniae , also induces specific histone modifications, including robust dephosphorylation of histone H3 on serine 10, during infection of respiratory epithelial cells. Two bacterial factors are important for the induction o...

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Literature Corpus work: 88282b2a-e544-5b34-9a02-19964d9cb75d
DOI: 10.1101/2020.01.14.905968

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