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Epithelial cells maintain memory of prior infection with Streptococcus pneumoniae through di-methylation of histone H3

2 Jul 2024

Abstract excerpt

Epithelial cells are the first point of contact for bacteria entering the respiratory tract. Streptococcus pneumoniae is an obligate human pathobiont of the nasal mucosa, carried asymptomatically but also the cause of severe pneumoniae. The role of the epithelium in maintaining homeostatic interactions or mounting an inflammatory response to invasive S. pneumoniae is currently poorly understood. However, studies...

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PMID: 38956024
DOI: 10.1038/s41467-024-49347-1

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