Article

Rare coding variants from ADSP R5 whole-genome sequencing implicate novel genes in Alzheimer’s disease

2026-03-31

Abstract excerpt

<title>Abstract</title> <p>The Alzheimer’s Disease Sequencing Project (ADSP) Release 5 provides whole-genome sequencing data from 58,507 individuals across diverse ancestries to discover rare coding variants and genes associated with Alzheimer’s disease (AD) and AD-related traits. Gene-based aggregation tests identified 40 genes surpassing a Bonferroni-corrected gene-wide significance threshold, including establi...

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Literature Corpus work: 8812ae6c-8ecb-568b-b494-b3422d17c207
DOI: 10.21203/rs.3.rs-9013646/v1

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