Article

Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer’s Diseases Sequencing Project Subjects

2023-10-05

Abstract excerpt

<title>Abstract</title> Structural variations (SVs) are important contributors to the genetics of human diseases. However, their role in Alzheimer’s disease (AD) remains largely unstudied due to challenges in accurately detecting SVs. We analyzed whole-genome sequencing data from the Alzheimer’s Disease Sequencing Project (N = 16,905) and identified 400,234 (168,223 high-quality) SVs. Laboratory validation yie...

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Literature Corpus work: 02a57a9e-84eb-5105-8027-5c1d755885db
DOI: 10.21203/rs.3.rs-3353179/v1

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