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Article

IL-13R130Q modulates human airway smooth muscle cell phenotype to contribute to severe asthma

2022-06-15

Abstract excerpt

<h4>Background: </h4> A small percentage of asthma patients experience severe and refractory asthma that responds poorly to standard therapy. However, this percentage is increasing and better treatment options are therefore needed. Our previous study showed that cultured human airway smooth muscle cells treated with IL-13 R130Q, a naturally occurring IL-13 variant, displayed enhanced functional activities compared...

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Literature Corpus work
87e529da-3c89-5eef-ad6d-7a9a1e04b9d1
DOI
10.21203/rs.3.rs-1741583/v1
Open publication

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