Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-13 Induces Dramatically Different Transcriptional Programs in Three Human Airway Cell Types

1 Oct 2001

Abstract excerpt

Interleukin (IL)-13, a cytokine released by T lymphocytes during immediate hypersensitivity responses, is a central mediator of asthma. Because IL-13 induces phenotypic features of asthma in mice deficient in T and B lymphocytes, it is likely that this cytokine contributes to the development of asthma by acting directly on resident airway cells. To analyze the global effects of IL-13 on gene expression in airway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to IL-33, ST2, and ILC Pathways
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11694453
DOI: 10.1165/ajrcmb.25.4.4522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-13 Induces Dramatically Different Transcriptional Programs in Three Human Airway Cell TypesPMID 11694453Read ↗

Genome-Wide Methylation Study Identifies an IL-13–induced Epigenetic Signature in Asthmatic AirwaysSemantic proximity Read ↗

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells.Semantic proximity Read ↗

Targeting a central feature of asthma using a cell type-selective IL-13-responsive enhancerSemantic proximity Read ↗

IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies.Semantic proximity Read ↗

IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin ProductionSemantic proximity Read ↗

Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lungSemantic proximity Read ↗

The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epitheliumSemantic proximity Read ↗

The gene encoding interleukin-13: a susceptibility locus for asthma and related traits.Semantic proximity Read ↗

The Cell Type-Specific Expression of the Murine <i>IL-13</i> Gene Is Regulated by GATA-3Semantic proximity Read ↗

IL-13 Induces Esophageal Remodeling and Gene Expression by an Eosinophil-Independent, IL-13Rα2–Inhibited PathwaySemantic proximity Read ↗

Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in AsthmaSemantic proximity Read ↗

IL-13 and its genetic variants: effect on current asthma treatments.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.