Article

The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice

2022-12-14

Abstract excerpt

Transposable elements constitute nearly half of the mammalian genome and play important roles in genome evolution. While a multitude of both transcriptional and post-transcriptional mechanisms exist to silence transposable elements, control of transposition in vivo remains poorly understood. MOV10, an RNA helicase, is a potent inhibitor of mobilization of retrotransposons and retroviruses in cell culture assays....

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Literature Corpus work: 87dde543-89e8-57ad-ba7d-965b93b096c1
DOI: 10.1101/2022.12.13.520206

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