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Article

HLA-disease association and pleiotropy landscape in over 235,000 Finns.

Human immunology - 1 May 2022

Ritari Jarmo, Koskela Satu, Hyvärinen Kati, FinnGen, Partanen Jukka

Abstract excerpt

The human leukocyte antigen (HLA) system is the single most important genetic susceptibility factor for many autoimmune diseases and immunological traits. For systematic population-level analysis of HLA-phenotype association landscape we imputed the alleles of classical HLA genes in a discovery cohort of 146,630 and replication cohort of 89,340 Finns of whom SNP genotype data and 3,355 disease phenotypes were...

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PMID: 35221124
DOI: 10.1016/j.humimm.2022.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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