Article

Novel Gurmarin-like Peptides from <i>Gymnema sylvestre</i> and their Interactions with the Sweet Taste Receptor T1R2/T1R3

2023-08-31

Abstract excerpt

Gymnema sylvestre (GS) is a traditional medicinal plant known for its hypoglycemic and hypolipidemic effects. Gurmarin (hereafter Gur-1) is the only known active peptide in GS. Gur-1 has a suppressive sweet taste effect in rodents but no or only a very weak effect in humans. Here, eight gurmarin-like peptides (Gur-2 to Gur-9) and their isoforms are reported in the GS transcriptome. The molecular mechanism of sweet...

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Literature Corpus work: 877106fa-7d31-5b11-b316-c9e2f97ff446
DOI: 10.1101/2023.08.28.555239

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Novel Gurmarin-like Peptides from <i>Gymnema sylvestre</i> and their Interactions with the Sweet Taste Receptor T1R2/T1R3DOI 10.1101/2023.08.28.555239Read

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