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Article

Bitter taste receptors establish a stable binding affinity with the SARS-CoV-2-spike 1 protein akin to ACE2.

Journal of biomolecular structure & dynamics - 1 May 2025

Kumar Senthil Arun, Selvaa Kumar C, Dsouza Norine

Abstract excerpt

COVID-19 is caused by the highly contagious SARS-CoV-2 virus, which originated in Wuhan, China, resulting in the highest worldwide mortality rate. Gustatory dysfunction is common among individuals infected with the Wild-type Wuhan strain. However, there are no reported cases of gustatory dysfunction among patients infected with the mutant delta variant. The reason behind this remains elusive to date. This...

Read the complete abstract on PubMed

Topics

Spike Glycoprotein, Coronavirus
Angiotensin-Converting Enzyme 2
Humans
SARS-CoV-2
Protein Binding
Receptors, G-Protein-Coupled

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Molecular Docking Simulation

COVID-19

Binding Sites

Mutation

Molecular Dynamics Simulation

Source

Identifiers

PMID: 38189335
DOI: 10.1080/07391102.2023.2300128

Genes

ACE2

Provenance

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