Article

Regulation of human development by ubiquitin chain editing of chromatin remodelers

2020-01-24

Abstract excerpt

Embryonic development occurs through commitment of pluripotent stem cells to differentiation programs that require highly coordinated changes in gene expression. Chromatin remodeling of gene regulatory elements is a critical component of how such changes are achieved. While many factors controlling chromatin dynamics are known, mechanisms of how different chromatin regulators are orchestrated during development ar...

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Literature Corpus work: 874ca654-1f1d-5b89-a8e3-492c36407e7c
DOI: 10.1101/2020.01.23.917450

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