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Article

Possible Involvement of Differential Ubiquitination as a Molecular Basis of Phenotypic Heterogeneity in Neurodevelopmental Disorders.

Genes - 5 May 2026

Nakagawa Tadashi, Nakagawa Makiko

Abstract excerpt

Neurodevelopmental disorders (NDDs) are characterized by remarkable phenotypic heterogeneity, in which individuals harboring mutations in the same gene display divergent clinical manifestations, ranging from mild cognitive impairment to severe neurodevelopmental deficits. Advances in neurogenetics and neurogenomics have rapidly expanded the catalog of genes associated with NDDs and have provided unprecedented...

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PMID: 42195010
DOI: 10.3390/genes17050553
PMCID: PMC13205836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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