Article

Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cells

2022-05-25

Abstract excerpt

In the human thymus, a CD10 + PD-1 + TCRαβ + differentiation pathway diverges from the conventional single positive T cell lineages at the early double positive stage. These cells are phenotypically and functionally similar to murine unconventional intraepithelial lymphocyte (uIEL) precursors. Here, the progeny of the human uIEL lineage was identified in antigen-inexperienced blood. The uIELs in thymus and peri...

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Literature Corpus work: 32b4eb2d-1553-5d26-a75d-9531765e76d4
DOI: 10.1101/2022.05.24.492634

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