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Article

Bayesian Inference of Allelic Inclusion Rates in the Human T Cell Receptor Repertoire.

Cell systems - 27 Nov 2019

Carter Jason A, Preall Jonathan B, Atwal Gurinder S

Abstract excerpt

A small population of αβ T cells is characterized by the expression of more than one unique T cell receptor (TCR); this outcome is the result of "allelic inclusion," that is, inclusion of both α- or β-chain alleles during V(D)J recombination. Limitations in single-cell sequencing technology, however, have precluded comprehensive enumeration of these dual receptor T cells. Here, we develop and experimentally...

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Source

Identifiers

PMID: 31677971
DOI: 10.1016/j.cels.2019.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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