Article

scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues

2024-12-30

Abstract excerpt

The rearrangement of TCR germline V(D)J genes during T cell development, including allelic exclusion and tolerance selection, ensures the clonal selection theory, which states that “a lymphocyte expresses only one type of antigen receptor” This forms the basis for T cell-specific responses. However, The existence of “dual TCR T cells” has consistently been supported by specific experimental evidence. detailed rep...

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Literature Corpus work: 06d5649b-990e-5cf6-9719-c0433fb77a70
DOI: 10.1101/2024.12.30.630731

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