Article

WITHDRAWN: GATA2 promotes castration-resistant prostate cancer development by suppressing IFN-β axis-mediated antitumor immunity

2024-02-23

Abstract excerpt

<title>Abstract</title> <p> Castration-resistant prostate cancer (CRPC) nearly inevitably develops after long-term treatment with androgen deprivation therapy (ADT), leading to significant mortality. Investigating the mechanisms driving CRPC development is imperative. Here, we determined that the pioneer transcription factor <italic>GATA2</italic> , which is frequently amplified in CRPC patients, inhibits inte...

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Literature Corpus work: 86f6cd3d-8389-5c76-bf38-479ddbfb04cc
DOI: 10.21203/rs.3.rs-3958845/v1

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