Article

Interferon-γ Increases Sensitivity to Chemotherapy and Provides Immunotherapy Targets in Models of Metastatic Castration-Resistant Prostate Cancer

2021-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Interferon-γ (IFNγ) is a cytokine with limited evidence of benefit in cancer clinical trials to date. However, it could potentially play a role in potentiating anti-tumor immunity in the immunologically “cold” metastatic castration-resistant prostate cancer (mCRPC) by inducing antigen presentation pathways and concurrently providing targets for immune checkpoint blockade therapy. Moreover, it co...

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Literature Corpus work: 81c9791b-6b3e-55f2-a925-3f52ecd18e10
DOI: 10.1101/2021.08.20.457028

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