Article

Cancer-driven IgG promotes the development of castration-resistant Prostate Cancer though the SOX2-CIgG pathway

2020-05-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Although Androgen deprivation therapy (ADT) is the initial treatment strategy for prostate cancer, recurrent castration-resistant prostate cancer (CRPC) eventually ensues. In this study, cancer-derived immunoglobulin G(CIgG) was found to be induced after ADT, identifying CIgG as a potential CRPC driver gene.<bold>Methods:</bold> The expression of CIgG and its cl...

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Literature Corpus work: e4be1237-5d1a-5f41-a796-a3e044b044bc
DOI: 10.21203/rs.3.rs-31159/v1

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