Article

Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD

2024-02-29

Abstract excerpt

The gene expression profiles of distinct cell types reflect complex genomic interactions among multiple simultaneous biological processes within each cell that can be altered by disease progression as well as genetic background. The identification of these active cellular programs is an open challenge in the analysis of single-cell RNA-seq data. Latent Dirichlet Allocation (LDA) is a generative method used to iden...

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Literature Corpus work: 86ec8d82-4a89-5dcd-9331-5d905b2078eb
DOI: 10.1101/2024.02.26.582178

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Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of ADDOI 10.1101/2024.02.26.582178Read

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