Article

scVIP: personalized modeling of single-cell transcriptomes for developmental and disease phenotypes

2026-04-22

Abstract excerpt

Single-cell transcriptomics resolves cellular heterogeneity within individuals, but connecting molecular states to individual-level phenotypes requires frameworks that explicitly bridge these scales. We present scVIP, a generative model that links gene expression, cell-type composition, and phenotypic measurements within a single probabilistic model, which enables accurate phenotype prediction and interpretable tr...

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Literature Corpus work: ed55be1c-1155-5ee9-86aa-32dce53d6043
DOI: 10.64898/2026.04.20.717759

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