Article
A lottery simulation model for predicting cancer risk based on the strength and abundance of individual mutations
2016-11-15
Abstract excerpt
Models for predicting an individual’s risk of developing cancer are complicated by a lack of well-conserved mutations present in most types of disease. To address this challenge we developed a simple lottery simulation of cancer development based solely on the abundance and relative survival advantage of mutations present within individual stem or progenitor cells. In simulations requiring few mutations or that in...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 86a9f22f-7eb4-5cf5-b2e3-500ecbc4ab93
- DOI
- 10.1101/087916