Article

An intact S-layer is advantageous to <i>Clostridioides difficile</i> within the host

2022-11-23

Abstract excerpt

Clostridioides difficile is responsible for substantial morbidity and mortality in antibiotically-treated, hospitalised, elderly patients, in which toxin production correlates with diarrhoeal disease. While the function of these toxins has been studied in detail, the contribution of other factors, including the paracrystalline surface layer (S-layer), to disease is less well known. Here, we highlight the essential...

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Literature Corpus work: a3576646-9892-53f7-8069-70a12fb54ee4
DOI: 10.1101/2022.11.22.517470

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