Article

Determinants in the HTLV-1 capsid major homology region that are critical for virus particle assembly

2024-04-07

Abstract excerpt

The Gag protein of retroviruses is the primary driver of virus particle assembly. Particle morphologies among retroviral genera are distinct, with intriguing differences observed relative to HIV-1, particularly that of human T-cell leukemia virus type 1 (HTLV-1). In contrast to HIV-1 and other retroviruses where the capsid (CA) carboxy-terminal domain (CTD) possesses the key amino acid determinants involved in dri...

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Literature Corpus work: 8636f606-6cd1-5fb4-8200-25a6330b4e41
DOI: 10.1101/2024.04.07.588439

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