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HIV-1 capsid and viral DNA integration

12 Dec 2023

Abstract excerpt

ABSTRACT The human immunodeficiency virus type 1 (HIV-1) genome encodes 15 proteins that perform structural, enzymatic, regulatory, and accessory functions. The capsid protein (CA) is the primary structural protein of HIV-1 and plays multiple functions during infection. Early studies predicted that HIV-1 CA mainly protected and delivered the viral genome to the target cell. However, it is now well established...

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PMID: 38085100
DOI: 10.1128/mbio.00212-22

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