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Article

Mutations in capsid major homology region affect assembly and membrane affinity of HIV-1 Gag.

Journal of molecular biology - 13 Jul 2007

Chang Yu-Fen, Wang Shiu-Mei, Huang Kuo-Jung, Wang Chin-Tien

Abstract excerpt

We introduced mutations into the HIV-1 major homology region (MHR; capsids 153-172) and adjacent C-terminal region to analyze their effects on virus-like particle (VLP) assembly, membrane affinity, and the multimerization of the Gag structural protein. Results indicate that alanine substitutions...

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Identifiers

PMID: 17532005
DOI: 10.1016/j.jmb.2007.05.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17532005-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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