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Article

Critical Role of the Human T-Cell Leukemia Virus Type 1 Capsid N-Terminal Domain for Gag-Gag Interactions and Virus Particle Assembly.

Journal of virology - 15 Jul 2018

Martin Jessica L, Mendonça Luiza M, Marusinec Rachel, Zuczek Jennifer, Angert Isaac, Blower Ruth J, Mueller Joachim D, Perilla Juan R, Zhang Wei, Mansky Louis M

Abstract excerpt

The retroviral Gag protein is the main structural protein responsible for virus particle assembly and release. Like human immunodeficiency virus type 1 (HIV-1) Gag, human T-cell leukemia virus type 1 (HTLV-1) has a structurally conserved capsid (CA) domain, including a β-hairpin turn and a centralized coiled-coil-like structure of six α helices in the CA amino-terminal domain (NTD), as well as four α-helices in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Identifiers

PMID: 29695435
DOI: 10.1128/JVI.00333-18
PMCID: PMC6026748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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