Article

Integrative clinical–genomic modeling evaluates exploratory Non-APOE candidate signals in Alzheimer’s disease

2026-08-21

Abstract excerpt

<title>Abstract</title> <p> Background Alzheimer’s disease (AD) is characterized by a genetic architecture dominated by <italic>APOE</italic> , while predictive modeling in clinically enriched cohorts is often driven by neuropsychological and clinical variables. This combination limits the interpretability of secondary genetic signals in multimodal frameworks. Methods We applied a two-stage Korean WES–WGS de...

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Literature Corpus work: 8615eceb-4498-5beb-a0e5-3a6a5be1c593
DOI: 10.21203/rs.3.rs-9617891/v1

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