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Article

Transferability of a European-derived Alzheimer’s Disease Genetic Risk Score across Multi-Ancestry Populations.

2023-11-07

Abstract excerpt

<title>Abstract</title> <p><bold>We built a genetic risk score (GRS) from the most complete landscape of the Alzheimer disease (AD) genetics. We extended its analysis in 16 European countries and observed a consistent association of this GRS with AD risk, age at onset and cerebrospinal fluid (CSF) AD biomarker levels regardless of the </bold><italic><bold>Apolipoprotein E (APOE) </bold></italic><bold>genotype. Th...

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Literature Corpus work
0c1d52b7-a209-5620-b425-68d370a13317
DOI
10.21203/rs.3.rs-3556205/v1
Open publication

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Transferability of a European-derived Alzheimer’s Disease Genetic Risk Score across Multi-Ancestry Populations.DOI 10.21203/rs.3.rs-3556205/v1
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