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The mutational signatures of poor treatment outcomes on the drug-susceptible <i>Mycobacterium tuberculosis</i> genome

2022-11-21

Abstract excerpt

<h4>ABSTRACT</h4> Drug resistance is a known risk factor for poor tuberculosis (TB) treatment outcomes, but the contribution of other bacterial factors to poor outcomes in drug susceptible TB is less understood. Here, we generate a population-based dataset of drug-susceptible Mycobacterium tuberculosis (MTB) isolates from China to identify factors associated with poor treatment outcomes. We sequenced the whole g...

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Literature Corpus work
85f2de24-4380-5c6e-8cca-186b21a939d6
DOI
10.1101/2022.11.20.517260
Open publication

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The mutational signatures of poor treatment outcomes on the drug-susceptible <i>Mycobacterium tuberculosis</i> genomeDOI 10.1101/2022.11.20.517260
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